Filters

Anti-DYRK1A (Polyclonal), ALEXA Fluor 594

Anti-DYRK1A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideDYRK1A
SpecificityThis antibody reacts specifically with DYRK1A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DYRK1A
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1A, Dyrk1A is a candidate gene for learning defects that are involved in Downs syndrome (DS), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, Four isoforms of Dyrk1A exist due to alternative splicing events, Localized to the nucleus and highly expressed in testis, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases, also known as MNB or MNBH, are thought to be involved in diverse cellular functions, functions to phosphorylate serine, including Dyrk1A (dual specificity tyrosine-phosphorylation-regulated kinase 1A), muscle and the developing nervous system, suggesting a possible role for Dyrk1A in the development of DS, threonine and tyrosine residues on various substrates involved in signaling pathways that regulate cell proliferation, which is itself regulated by tyrosine phosphorylation, Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene which is required for neurogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asDYRK1A Polyclonal Antibody
Other nameAnti-DYRK1A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetDYRK1A
Short nameAnti-DYRK1A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-DYRK1A (polyclonal)
Alternative techniquepolyclonals
Identity 3091
Gene DYRK1A
Long gene name dual specificity tyrosine phosphorylation regulated kinase 1A
Synonyms gene DYRK1 DYRK MNBH
Synonyms gene name dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
Locus 21q22, 13
Discovery year 1999-01-29
GenBank acession U52373
Entrez gene record 1859
Pubmed identfication 9284911
RefSeq identity NM_001396
Havana BLAST/BLAT OTTHUMG00000086657

Similar products

Subscribe to our Newsletter