Anti-EDA (Polyclonal), ALEXA Fluor 594

Anti-EDA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	EDA/Ectodermal dysplasia protein
Specificity	This antibody reacts specifically with EDA
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	membrane form/secreted form, KLH conjugated synthetic peptide derived from human Ectodysplasin-A
Gene ID	1896
Swiss Prot	N/A
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	EDA is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation, EDA is a type II membrane protein which forms trimers, EDA is expressed in hair follicles and in the epidermis of adult skin, Ectodysplasin A (EDA) is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells, Similar to other members of collagenous membrane proteins and members of TNF-related ligands, Some of the patients reported by Halperin and Curtis showed mental defect also, The sequence of the longest isoform includes an interrupted collagenous domain of 19 Gly-X-Y repeats and a motif conserved in the tumor necrosis factor (TNF)-related ligand family, abnormal teeth and absent sweat glands, but this is not an invariable feature, Affected males of X-linked anhidrotic ectodermal dysplasia show hypotrichosis
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	EDA1 XLHED HED XHED ED1-A1 ED1-A2 EDA-A1 EDA-A2
Also known as	EDA Polyclonal Antibody
Other name	Anti-EDA Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	EDA
Short name	Anti-EDA (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-ectodysplasin A (polyclonal)
Alternative technique	polyclonals
Alternative to gene target	ECTD1 and ED1 and ED1-A1 and ED1-A2 and EDA-A1 and EDA-A2 and EDA1 and EDA2 and HED and HED1 and ODT1 and STHAGX1 and XHED and XLHED, EDA and IDBG-636361 and ENSBTAG00000012543 and 616179, EDA and IDBG-74170 and ENSG00000158813 and 1896, Eda and IDBG-161929 and ENSMUSG00000059327 and 13607, Extracellular, protein binding, this GO :0001942 and hair follicle development and biological process this GO :0005102 and receptor binding and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007398 and ectoderm development and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030154 and cell differentiation and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043473 and pigmentation and biological process this GO :0043588 and skin development and biological process this GO :0045177 and apical part of cell and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0060662 and salivary gland cavitation and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061153 and trachea gland development and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, ectodysplasin A
Identity	3157
Gene	EDA
Long gene name	ectodysplasin A
Synonyms gene	ED1 EDA2 ODT1
Synonyms gene name	anhidrotic oligodontia 1 , ectodermal dysplasia 1
Locus	Xq13, 1
Discovery year	2001-06-22
GenBank acession	U59227
Entrez gene record	1896
Pubmed identfication	8696334 18657636 16583127
RefSeq identity	NM_001399
Classification	Tumor necrosis factor superfamily
Havana BLAST/BLAT	OTTHUMG00000021764
Locus Specific Databases	Mental Retardation database

Anti-EDA (Polyclonal), ALEXA Fluor 594

Anti-EDA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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