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Anti-EFEMP2/Fibulin 4 (Polyclonal), ALEXA Fluor 594

Anti-EFEMP2/Fibulin 4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEFEMP2/Fibulin 4
SpecificityThis antibody reacts specifically with EFEMP2/Fibulin 4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4
Gene ID30008
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), Expressed ubiquitously with highest expression in heart, Fibulin-4, Fibulin-4 is essential for connective tissue development and elastic fiber formation, MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family, a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), and may also play an important role in vascular patterning and collagen biosynthesis, lung and skin, such as vasculature, Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FBLN4 UPH1
Also known asEFEMP2/Fibulin 4 Polyclonal Antibody
Other nameAnti-EFEMP2/Fibulin 4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEFEMP2/Fibulin 4
Short nameAnti-EFEMP2/Fibulin 4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-EFEMP2/Fibulin 4 (polyclonal)
Alternative techniquepolyclonals
Identity 3219
Gene EFEMP2
Long gene name EGF containing fibulin like extracellular matrix protein 2
Synonyms gene name EGF-containing fibulin-like extracellular matrix protein 2
Synonyms name fibulin 4
Locus 11q13, 1
Discovery year 2000-03-01
GenBank acession AF109121
Entrez gene record 30008
Pubmed identfication 10601734 10982184
RefSeq identity NM_016938
Classification Fibulins
Havana BLAST/BLAT OTTHUMG00000166664

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