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Anti-EFHC2 (Polyclonal), ALEXA Fluor 594

Anti-EFHC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEFHC2
SpecificityThis antibody reacts specifically with EFHC2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human EFHC2
Gene ID80258
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Deletion of the EF-HC2 gene may be associated with Norrie disease, EF-HC2 exists as two isoforms due to alternative splicing events, EF-HC2 shares 41, EFHC2 can be used as a quantitative trait locus for fear recognition in Turner syndrome, The gene encoding EF-HC2 maps to human chromosome Xp11, There are two named isoforms produced by alternative splicing, Turner syndrome, an X-linked disorder that primarily effects the eye, and is widely expressed in peripheral tissues and central nervous system, and may also be linked to juvenile myoclonic epilepsy, characterized by deficits in social cognition and recognition of facial fear, followed by 3 putative EF-hand motifs, has been linked to the EF-HC2 gene, 3 and is critical for recognition of facial fear and harm avoidance, 6% homology with EF-HC1, EF-HC2 is a 749 amino acid protein containing three DM10 domains and an EF-hand domain, EFHC2 contains 3 DM10 domains
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ22843
Also known asEFHC2 Polyclonal Antibody
Other nameAnti-EFHC2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEFHC2
Short nameAnti-EFHC2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-EFHC2 (polyclonal)
Alternative techniquepolyclonals
Identity 26233
Gene EFHC2
Long gene name EF-hand domain containing 2
Synonyms gene MRX74
Synonyms gene name X-linked 74 EF-hand domain (C-terminal) containing 2 , mental retardation
Locus Xp11, 3
Discovery year 2004-09-02
GenBank acession AK026254
Entrez gene record 80258
Pubmed identfication 17221867
RefSeq identity NM_025184
Classification X-linked mental retardation EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000021393
Locus Specific Databases Mental Retardation database

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