Name : Anti-EFHC2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4184307592
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | EFHC2 |
| Specificity | This antibody reacts specifically with EFHC2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human EFHC2 |
| Gene ID | 80258 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Deletion of the EF-HC2 gene may be associated with Norrie disease, EF-HC2 exists as two isoforms due to alternative splicing events, EF-HC2 shares 41, EFHC2 can be used as a quantitative trait locus for fear recognition in Turner syndrome, The gene encoding EF-HC2 maps to human chromosome Xp11, There are two named isoforms produced by alternative splicing, Turner syndrome, an X-linked disorder that primarily effects the eye, and is widely expressed in peripheral tissues and central nervous system, and may also be linked to juvenile myoclonic epilepsy, characterized by deficits in social cognition and recognition of facial fear, followed by 3 putative EF-hand motifs, has been linked to the EF-HC2 gene, 3 and is critical for recognition of facial fear and harm avoidance, 6% homology with EF-HC1, EF-HC2 is a 749 amino acid protein containing three DM10 domains and an EF-hand domain, EFHC2 contains 3 DM10 domains |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ22843 |
| Also known as | EFHC2 Polyclonal Antibody |
| Other name | Anti-EFHC2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | EFHC2 |
| Short name | Anti-EFHC2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-EFHC2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 26233 |
| Gene | EFHC2 |
| Long gene name | EF-hand domain containing 2 |
| Synonyms gene | MRX74 |
| Synonyms gene name | X-linked 74 EF-hand domain (C-terminal) containing 2 , mental retardation |
| Locus | Xp11, 3 |
| Discovery year | 2004-09-02 |
| GenBank acession | AK026254 |
| Entrez gene record | 80258 |
| Pubmed identfication | 17221867 |
| RefSeq identity | NM_025184 |
| Classification | X-linked mental retardation EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000021393 |
| Locus Specific Databases | Mental Retardation database |