Anti-EGR2 (Polyclonal), ALEXA Fluor 594

Anti-EGR2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	EGR2
Specificity	This antibody reacts specifically with EGR2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human EGR2
Gene ID	1959
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	CHN is characterized clinically by early onset of hypotonia, DSS patients exhibit severe early onset motor and sensory neuropathy with very slow nerve conduction velocities and elevated cerebrospinal fluid protein concentrations, Defects in the Egr-2 protein are a cause of congenital hypomyelination neuropathy (CHN), Egr-2 is a sequence-specific DNA-binding transcription factor that binds two specific DNA sites located in the promoter region of HoxA4 and localizes to the nucleus, Mutations in the gene that encodes Egr-2 (EGR2) also cause Dejerine-Sottas syndrome (DSS), The deduced amino acid sequences of human Egr-2 and mouse Egr-1 are 92% identical in the zinc finger region but show no homology elsewhere, areflexia, differentiation and function, distal muscle weakness and very slow nerve conduction velocities, which is also known as Dejerine-Sottas neuropathy (DSN) or hereditary motor and sensory neuropathy III (HMSN3), Egr proteins function in transcription regulatory activities surrounding cellular growth
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	EGR2 Polyclonal Antibody
Other name	Anti-EGR2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	EGR2
Short name	Anti-EGR2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-EGR2 (polyclonal)
Alternative technique	polyclonals
Identity	3239
Gene	EGR2
Long gene name	early growth response 2
Synonyms gene	KROX20
Synonyms gene name	Drosophila) , early growth response 2 (Krox-20 homolog
Synonyms name	Drosophila , Krox-20 homolog
Locus	10q21, 3
Discovery year	1988-08-31
GenBank acession	BC035625
Entrez gene record	1959
RefSeq identity	NM_000399
Classification	Zinc fingers C2H2-type
Havana BLAST/BLAT	OTTHUMG00000018308
Locus Specific Databases	Mutation Database of Inherited Peripheral Neuropathies LRG_239

Anti-EGR2 (Polyclonal), ALEXA Fluor 594

Anti-EGR2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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