Name : Anti-eIF6/ITGB4BP (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8673295012
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | e6/ITGB4BP |
| Specificity | This antibody reacts specifically with eIF6/ITGB4BP |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human eIF6 |
| Gene ID | 3692 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), Multiple transcript variants encoding several different isoforms have been found for this gene, The encoded protein, The protein encoded by Intergrin beta 4 binding protein binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton, a protein containing two fibronectin type III domains, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits, which is insoluble and found both in the nucleus and in the cytoplasm, Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | p27BBP b(2)gcn |
| Also known as | eIF6/ITGB4BP Polyclonal Antibody |
| Other name | Anti-eIF6/ITGB4BP Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | eIF6/ITGB4BP |
| Short name | Anti-eIF6/ITGB4BP (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-eIF6/ITGB4BP (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 6159 |
| Gene | EIF6 |
| Long gene name | eukaryotic translation initiation factor 6 |
| Synonyms gene | EIF3A ITGB4BP |
| Synonyms gene name | integrin beta 4 binding protein |
| Locus | 20q11, 22 |
| Discovery year | 1998-03-24 |
| GenBank acession | Y11435 |
| Entrez gene record | 3692 |
| Pubmed identfication | 9374518 9740680 |
| RefSeq identity | NM_002212 |
| Havana BLAST/BLAT | OTTHUMG00000032328 |