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Anti-ELAVL2 + ELAVL4 (Polyclonal), ALEXA Fluor 594

Anti-ELAVL2 + ELAVL4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideELAVL2 + ELAVL4
SpecificityThis antibody reacts specifically with ELAVL2 + ELAVL4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ELAVL2
Gene ID1993, 1996
Swiss ProtP25378, Q12926
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation, An additional mammalian homolog, Characteristically, Elav, Elav proteins function within the nucleus, HuD and Hel-N1, HuR, Several mammalian Elav-like proteins, When Elav-like proteins associate with these ARE sites this degradation is inhibited, a Drosophila protein and the first described member, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, are also expressed in postmitotic neurons, designated HuC, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance, is ubiquitously expressed and is also overexpressed in a wide variety of tumors, leading to an increased stability of the corresponding transcript, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites, which is also designated HuA, The Elav-like genes encode for a family of RNA-binding proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PNEM
Also known asELAVL2 + ELAVL4 Polyclonal Antibody
Other nameAnti-ELAVL2 + ELAVL4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetELAVL2 + ELAVL4
Short nameAnti-ELAVL2 + ELAVL4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ELAVL2 and ELAVL4 (polyclonal)
Alternative techniquepolyclonals
Identity 3315
Gene ELAVL4
Long gene name ELAV like RNA binding protein 4
Synonyms gene HUD
Synonyms gene name Drosophila)-like 4 (Hu antigen D) ELAV (embryonic lethal, Drosophila)-like 4 ELAV like neuron-specific RNA binding protein 4 , ELAV (embryonic lethal, abnormal vision, abnormal vision
Synonyms name Hu antigen D
Locus 1p33-p32, 3
Discovery year 1993-07-12
GenBank acession AY033998
Entrez gene record 1996
Pubmed identfication 8222755
RefSeq identity NM_021952
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000007877

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