Name : Anti-ELL3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1724169384
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ELL3 |
| Specificity | This antibody reacts specifically with ELL3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ELL3 |
| Gene ID | 80237 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ELL (11-19 lysine-rich leukemia protein), ELL is abundantly expressed in peripheral blood leukocytes, ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II, ELL3 is exclusively expressed in testis, Elongation is thought to be a critical stage for the regulation of gene expression, It is also thought to regulate cellular proliferation, This is a multistep process, Though similar to ELL and ELL2, also designated MEN, brain, called the transcription cycle, clearance, elongation and termination, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II, heart, kidney, liver and ovary, lung, placenta and testis, promoter, skeletal muscle, that includes five stages: preinitiation, thymus, with lower expression in spleen, Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ22637 |
| Also known as | ELL3 Polyclonal Antibody |
| Other name | Anti-ELL3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ELL3 |
| Short name | Anti-ELL3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ELL3 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 23113 |
| Gene | ELL3 |
| Long gene name | elongation factor for RNA polymerase II 3 |
| Synonyms gene name | elongation factor RNA polymerase II-like 3 |
| Locus | 15q15, 3 |
| Discovery year | 2003-09-17 |
| GenBank acession | AF276512 |
| Entrez gene record | 80237 |
| Pubmed identfication | 10882741 |
| RefSeq identity | NM_025165 |
| Classification | Super elongation complex |
| Havana BLAST/BLAT | OTTHUMG00000059936 |