Name : Anti-ELMO1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9378758746
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ELMO1 |
| Specificity | This antibody reacts specifically with ELMO1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ELMO |
| Gene ID | 9844 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases, It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1, ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0281 CED12 ELMO-1 CED-12 |
| Also known as | ELMO1 Polyclonal Antibody |
| Other name | Anti-ELMO1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ELMO1 |
| Short name | Anti-ELMO1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-engulfment and cellular motility 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CED-12 and CED12 and ELMO-1, ELMO1 and IDBG-12649 and ENSG00000155849 and 9844, ELMO1 and IDBG-633074 and ENSBTAG00000003490 and 509821, Elmo1 and IDBG-132929 and ENSMUSG00000041112 and 140580, Plasma membranes, SH3 domain binding, engulfment and biological process this GO :0006915 and apoptotic process and biological process this GO :0006928 and cellular component movement and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0030029 and actin filament-based process and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0045087 and innate immune response and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process, this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0006911 and pha this GO cytosis, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, engulfment and cell motility 1 |
| Identity | 16286 |
| Gene | ELMO1 |
| Long gene name | engulfment and cell motility 1 |
| Synonyms gene name | C, elegans) , engulfment and cell motility 1 (ced-12 homolog |
| Locus | 7p14, 1 , 2-p14 |
| Discovery year | 2001-12-13 |
| GenBank acession | AF398885 |
| Entrez gene record | 9844 |
| Pubmed identfication | 11595183 |
| RefSeq identity | NM_130442 |
| Classification | Engulfment and cell motility proteins |
| Havana BLAST/BLAT | OTTHUMG00000023701 |