Anti-Emerin (Polyclonal), ALEXA Fluor 594

Anti-Emerin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Emerin
Specificity	This antibody reacts specifically with Emerin
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human Emerin
Gene ID	2010
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway, Association of EMD with the viral DNA requires the presence of BAF and viral integrase, EMD and BAF are cooperative cofactors of HIV-1 infection, Inhibits beta-catenin activity by preventing its accumulation in the nucleus, Links centrosomes to the nuclear envelope via a microtubule association, Required for proper localization of non-farnesylated prelamin-A/C, Skeletal muscle, Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments, The association of viral DNA with chromatin requires the presence of BAF and EMD, colon, heart, ovary and pancreas, testis, Stabilizes and promotes the formation of a nuclear actin cortical network, Tissue specificity
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	STA LEMD5
Also known as	Emerin Polyclonal Antibody
Other name	Anti-Emerin Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Emerin
Short name	Anti-Emerin (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Emerin (polyclonal)
Alternative technique	polyclonals
Identity	3331
Gene	EMD
Long gene name	emerin
Synonyms gene name	Emery-Dreifuss muscular dystrophy
Synonyms name	LEM domain containing 5
Locus	Xq28
Discovery year	2001-06-22
GenBank acession	X82434
Entrez gene record	2010
Classification	LEM domain containing
Havana BLAST/BLAT	OTTHUMG00000033186
Locus Specific Databases	Leiden Muscular Dystrophy Pages UMD Locus Specific Databases Leiden Muscular Dystrophy pages Mental Retardation database LRG_745

Anti-Emerin (Polyclonal), ALEXA Fluor 594

Anti-Emerin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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