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Anti-EML4 (Polyclonal), ALEXA Fluor 594

Anti-EML4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEML4
SpecificityThis antibody reacts specifically with EML4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human EML4/C2orf180
Gene ID27436
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information C2orf2 or ROPP120, Due to a chromosomal inversion with chromosome 2p, ELP120, EML4 (Echinoderm microtubule-associated protein-like 4), EML4 is thought to modify the assembly dynamics of microtubules, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules, Expressed at high levels during mitosis, also known as EMAPL4, cell motility, is a 981 amino acid cytoplasmic protein that contains nine WD repeats, producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer, specifically altering microtubules to become longer and more flexible, spindle formation and chromosome movements, Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ROPP120 ELP120
Also known asEML4 Polyclonal Antibody
Other nameAnti-EML4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEML4
Short nameAnti-EML4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-EML4 (polyclonal)
Alternative techniquepolyclonals
Identity 1316
Gene EML4
Long gene name echinoderm microtubule associated protein like 4
Synonyms gene C2orf2
Locus 2p21
Discovery year 2000-01-31
GenBank acession AF177377
Entrez gene record 27436
RefSeq identity NM_019063
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000128603

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