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Anti-EMP1 (Polyclonal), ALEXA Fluor 594

Anti-EMP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEMP1
SpecificityThis antibody reacts specifically with EMP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCell membrane
Antigen SourceKLH conjugated synthetic peptide derived from mouse Emp1
Gene ID13730
Swiss ProtP47801
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Mouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing, EMP-1 is very similar in structure to its close relative, EMP-1 may also be an important regulator in cell communication, EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer, It is a member of a small family of epithelial membrane proteins, It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border, Peripheral Myelin Protein 22 (PMP22), S phase is arrested and G1 phase is prolonged in esophogeal cancer cells, When EMP-1 is overexpressed, and adhesion, cell proliferation is inhibited, signaling, Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms TMP CL-20
Also known asEMP1 Polyclonal Antibody
Other nameAnti-EMP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEMP1
Short nameAnti-EMP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-EMP1 (polyclonal)
Alternative techniquepolyclonals
Identity 3333
Gene EMP1
Long gene name epithelial membrane protein 1
Locus 12p13, 1
Discovery year 1997-12-05
GenBank acession U43916
Entrez gene record 2012
Pubmed identfication 8996089 9126480
RefSeq identity NM_001423
Havana BLAST/BLAT OTTHUMG00000168775

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