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Anti-EMR1 (Polyclonal), ALEXA Fluor 594

Anti-EMR1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEMR1
SpecificityThis antibody reacts specifically with EMR1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human EMR1
Gene ID2015
Swiss ProtQ14246
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, EMR2, EMR3, F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5, FIRE, The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1, The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, The function of F4/80/EMR1 is unclear, These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and ETL (1â, and Langerhans cells in the skin (1), and are predominantly expressed on cells of the immune system (1â, brain microglia, but it is speculated to be involved in macrophage adhesion events, cell migration, designated F4/80 in mouse), gut lamina propria, including Kupffer cells in liver, or as a G-protein coupled signaling component of macrophages, splenic red pulp macrophages, which includes CD97, &euro, &euro, &ldquo, &ldquo, 3, 3), 3), 4), 6), The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asEMR1 Polyclonal Antibody
Other nameAnti-EMR1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetEMR1
Short nameAnti-EMR1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, hormone receptor-like 1 (polyclonal), mucin-like, antibody to-epidermal growth factor-like module containing
Alternative techniquepolyclonals
Alternative to gene target Cell surfaces, EMR1 and IDBG-22184 and ENSG00000174837 and 2015, EMR1 and IDBG-643875 and ENSBTAG00000007901 and, Emr1 and IDBG-194190 and ENSMUSG00000004730 and 13733, TM7LN3, hormone receptor-like 1, mucin-like, protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071944 and cell periphery and cellular component, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding, this GO :0004930: G-protein coupled receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, egf-like module containing
Identity 3336
Gene ADGRE1
Long gene name adhesion G protein-coupled receptor E1
Synonyms gene TM7LN3 EMR1
Synonyms gene name egf-like module containing, hormone receptor-like 1 , hormone receptor-like sequence 1 egf-like module containing, mucin-like, mucin-like
Locus 19p13, 2 , 3-p13
Discovery year 1994-08-31
GenBank acession X81479
Entrez gene record 2015
Pubmed identfication 7601460 9500513 25713288
Classification Adhesion G protein-coupled receptors, subfamily E
Havana BLAST/BLAT OTTHUMG00000181966

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