Name : Anti-EMR1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4876793375
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | EMR1 |
| Specificity | This antibody reacts specifically with EMR1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human EMR1 |
| Gene ID | 2015 |
| Swiss Prot | Q14246 |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, EMR2, EMR3, F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5, FIRE, The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1, The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, The function of F4/80/EMR1 is unclear, These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and ETL (1â, and Langerhans cells in the skin (1), and are predominantly expressed on cells of the immune system (1â, brain microglia, but it is speculated to be involved in macrophage adhesion events, cell migration, designated F4/80 in mouse), gut lamina propria, including Kupffer cells in liver, or as a G-protein coupled signaling component of macrophages, splenic red pulp macrophages, which includes CD97, &euro, &euro, &ldquo, &ldquo, 3, 3), 3), 4), 6), The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | EMR1 Polyclonal Antibody |
| Other name | Anti-EMR1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | EMR1 |
| Short name | Anti-EMR1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, hormone receptor-like 1 (polyclonal), mucin-like, antibody to-epidermal growth factor-like module containing |
| Alternative technique | polyclonals |
| Alternative to gene target | Cell surfaces, EMR1 and IDBG-22184 and ENSG00000174837 and 2015, EMR1 and IDBG-643875 and ENSBTAG00000007901 and, Emr1 and IDBG-194190 and ENSMUSG00000004730 and 13733, TM7LN3, hormone receptor-like 1, mucin-like, protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071944 and cell periphery and cellular component, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding, this GO :0004930: G-protein coupled receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, egf-like module containing |
| Identity | 3336 |
| Gene | ADGRE1 |
| Long gene name | adhesion G protein-coupled receptor E1 |
| Synonyms gene | TM7LN3 EMR1 |
| Synonyms gene name | egf-like module containing, hormone receptor-like 1 , hormone receptor-like sequence 1 egf-like module containing, mucin-like, mucin-like |
| Locus | 19p13, 2 , 3-p13 |
| Discovery year | 1994-08-31 |
| GenBank acession | X81479 |
| Entrez gene record | 2015 |
| Pubmed identfication | 7601460 9500513 25713288 |
| Classification | Adhesion G protein-coupled receptors, subfamily E |
| Havana BLAST/BLAT | OTTHUMG00000181966 |