Anti-Endothelin 3 (Polyclonal), ALEXA Fluor 594

Anti-Endothelin 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Endothelin 3
Specificity	This antibody reacts specifically with Endothelin 3
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human ET-3
Gene ID	1908
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Mutations in Endothelin 3 and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), The active peptide binds endothelin receptor type B (EDNRB), This interaction EDNRB regulates the development of neural crest-derived cell lineages, such as melanocytes and enteric neurons, which are congenital disorders involving neural crest-derived cells, Endothelins are vasoactive proteins derived form the endothelium The active form of this protein is a 21aa peptide processed from the precursor
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	ET3
Also known as	Endothelin 3 Polyclonal Antibody
Other name	Anti-Endothelin 3 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Endothelin 3
Short name	Anti-Endothelin 3 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Endothelin 3 (polyclonal)
Alternative technique	polyclonals
Identity	3178
Gene	EDN3
Long gene name	endothelin 3
Locus	20q13, 32
Discovery year	1989-09-06
GenBank acession	X52001
Entrez gene record	1908
RefSeq identity	NM_000114
Classification	Endogenous ligands
Havana BLAST/BLAT	OTTHUMG00000032867
Locus Specific Databases	LOVD - Leiden Open Variation Database

Anti-Endothelin 3 (Polyclonal), ALEXA Fluor 594

Anti-Endothelin 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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