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Anti-ENSA/ARPP-19 (Polyclonal), ALEXA Fluor 594

Anti-ENSA/ARPP-19 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideENSA/ARPP-19
SpecificityThis antibody reacts specifically with ENSA/ARPP-19
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ENSA/ARPP-19
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ENSA/ARPP-19, ENSA/ARPP-19 is an endogenous regulator of the Î, ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms, It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients, Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, also known as ARPP-19e, cells, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family, ², ², -cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic Î, 3, Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC4319 MGC8394 MGC78563 ARPP-19e
Also known asENSA/ARPP-19 Polyclonal Antibody
Other nameAnti-ENSA/ARPP-19 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetENSA/ARPP-19
Short nameAnti-ENSA/ARPP-19 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ENSA/ARPP-19 (polyclonal)
Alternative techniquepolyclonals
Identity 3360
Gene ENSA
Long gene name endosulfine alpha
Locus 1q21, 3
Discovery year 1998-08-21
GenBank acession X99906
Entrez gene record 2029
Pubmed identfication 9653196
RefSeq identity NM_207042
Havana BLAST/BLAT OTTHUMG00000035004

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