Name : Anti-Ephexin-1/EPHEXIN (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5997574085
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Ephexin-1/EPHEXIN |
| Specificity | This antibody reacts specifically with Ephexin-1/EPHEXIN |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human EPHEXIN |
| Gene ID | 25791 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, EPHEXIN is subject to Src-dependent phosphorylation, Expressed at high levels in brain and present at lower levels in lung tissue, Human EPHEXIN, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse, an event that increases the GEF activity of EPHEXIN toward Rho A, one PH domain and one DH domain, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species, which exists as multiple alternatively spliced isoforms, EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | EPHEXIN, Eph-interacting exchange protein, Ephexin 1, NGEF_HUMAN, Neuronal guanine nucleotide exchange factor, Ngef, ARHGEF27 |
| Also known as | Ephexin-1/EPHEXIN Polyclonal Antibody |
| Other name | Anti-Ephexin-1/EPHEXIN Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Ephexin-1/EPHEXIN |
| Short name | Anti-Ephexin-1/EPHEXIN (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Ephexin-1/EPHEXIN (polyclonal) |
| Alternative technique | polyclonals |