Name : anti-ERGIC53 Monoclonal Antibody
Supplier : PROSCIENCE
Price :180
SKU : GEN4834978457
| Gene info | Mutations in the gene are associated with a coagulation defect, The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells, Using positional cloning, a rare, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, autosomal recessive disorder in which both coagulation factors V and VIII are diminished, presumably recycling between the two compartments, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, ERGIC53 Monoclonal Antibody: ERGIC53 |
| Gene names | ERGIC-53, F5F8D, FMFD1, LMAN1, MCFD1, MR60, endoplasmic reticulum-golgi intermediate compartment protein 53, gp58, ERGIC53 Monoclonal Antibody: Lectin mannose-binding 1 |
| Antibodie's label | unlabelled serum |
| Purity | ERGIC53 Monoclonal Antibody is affinity chromatography purified via peptide column |
| Ab raised in | Rabbit |
| Type | Monoclonal |
| Immunoglobulin | IgG1 |
| Spicific to | At least two isoforms of ERGIC53 are known to exist |
| Antigen | Mouse monoclonal ERGIC53 antibody was made against a 19 amino acid peptide near the carboxy terminus of human ERGIC53 |
| Immuno application | Western Blot, ELISA |
| Antibody advice | ERGIC53 antibody can be used for detection of ERGIC53 by Western blot at 1 - 2 ug/mL |
| Suspention, pH, azide | 02% sodium azide, ERGIC53 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for up to one year, ERGIC53 Monoclonal antibody can be stored at 4 grades C for three months and -20 grades C |
| Works with | Mouse, Human |
| Omim nr | 5031873 |
| Ncbi nr | NP_005561 |
| KDa | Predicted: 56 kDa |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 3998 |
| GENE symbol | LMAN1 |
| Antigene name | 1, mannose-binding, lectin |
| Source | homo sapiens |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | ERGIC53 Monoclonal |
| Short name | anti-ERGIC53 Monoclonal Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-ERGIC53 monoclonal (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6631 |
| Gene | LMAN1 |
| Long gene name | lectin, mannose binding 1 |
| Synonyms gene | F5F8D |
| Synonyms gene name | 1 , coagulation factor V-factor VIII combined deficiency lectin, mannose-binding |
| Synonyms | MR60 ERGIC-53 ERGIC53 gp58 MCFD1 FMFD1 |
| Synonyms name | endoplasmic reticulum-golgi intermediate compartment protein 53 |
| Locus | 18q21, 32 |
| Discovery year | 1996-06-06 |
| GenBank acession | X71661 |
| Entrez gene record | 3998 |
| Pubmed identfication | 9546392 8854877 |
| RefSeq identity | NM_005570 |
| Havana BLAST/BLAT | OTTHUMG00000132758 |
| Locus Specific Databases | LRG_595 |