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Anti-ERMAP (Polyclonal), ALEXA Fluor 594

Anti-ERMAP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideERMAP
SpecificityThis antibody reacts specifically with ERMAP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human ERMAP
Gene ID114625
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system, Expressed in cord blood, The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion, These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child, This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, fetal liver and adult bone marrow, infant death, ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BTN5
Also known asERMAP Polyclonal Antibody
Other nameAnti-ERMAP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetERMAP
Short nameAnti-ERMAP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-erythroblast membrane-associated protein (Scianna blood family) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target ERMAP and IDBG-97277 and ENSG00000164010 and 114625, Ermap and IDBG-182483 and ENSMUSG00000028644 and 27028, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, erythroblast membrane-associated protein (Scianna blood group)
Identity 15743
Gene ERMAP
Long gene name erythroblast membrane associated protein (Scianna blood group)
Synonyms gene RD SC
Synonyms gene name Radin blood group Scianna blood group erythroblast membrane-associated protein erythroblast membrane-associated protein (RD and SC blood groups) erythroblast membrane-associated protein (Scianna blood group)
Locus 1p34, 2
Discovery year 2001-09-06
GenBank acession AF311284
Entrez gene record 114625
Pubmed identfication 11549310
RefSeq identity NM_018538
Classification V-set domain containing Blood group antigens Butyrophilins
Havana BLAST/BLAT OTTHUMG00000007619
Locus Specific Databases Blood Group Antigen Mutation Database LRG_806

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