Name : Anti-ERMAP (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7402671557
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ERMAP |
| Specificity | This antibody reacts specifically with ERMAP |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human ERMAP |
| Gene ID | 114625 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system, Expressed in cord blood, The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion, These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child, This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, fetal liver and adult bone marrow, infant death, ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | BTN5 |
| Also known as | ERMAP Polyclonal Antibody |
| Other name | Anti-ERMAP Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ERMAP |
| Short name | Anti-ERMAP (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-erythroblast membrane-associated protein (Scianna blood family) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | ERMAP and IDBG-97277 and ENSG00000164010 and 114625, Ermap and IDBG-182483 and ENSMUSG00000028644 and 27028, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, erythroblast membrane-associated protein (Scianna blood group) |
| Identity | 15743 |
| Gene | ERMAP |
| Long gene name | erythroblast membrane associated protein (Scianna blood group) |
| Synonyms gene | RD SC |
| Synonyms gene name | Radin blood group Scianna blood group erythroblast membrane-associated protein erythroblast membrane-associated protein (RD and SC blood groups) erythroblast membrane-associated protein (Scianna blood group) |
| Locus | 1p34, 2 |
| Discovery year | 2001-09-06 |
| GenBank acession | AF311284 |
| Entrez gene record | 114625 |
| Pubmed identfication | 11549310 |
| RefSeq identity | NM_018538 |
| Classification | V-set domain containing Blood group antigens Butyrophilins |
| Havana BLAST/BLAT | OTTHUMG00000007619 |
| Locus Specific Databases | Blood Group Antigen Mutation Database LRG_806 |