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Anti-Estrogen receptor beta, PE

Anti-Estrogen receptor beta, PE size: 100 microliters 543

Price 543
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated withPE
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEstrogen receptor beta
SpecificityThis antibody reacts specifically with Estrogen receptor beta PE
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human ER-beta
Gene ID2100
Swiss ProtQ92731
ApplicationsFCM
Applications with corresponding dilutionsFCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds estrogens with an affinity similar to that of ESR1, DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual, Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner, Nuclear hormone receptor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission480, 565nm/578nm
Synonyms ER-BETA, ESR-BETA, ESR2, ESRB, ESTRB, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2, Erb
Also known asEstrogen receptor beta Antibody PE
Other nameAnti-Estrogen receptor beta PE
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene target PE, Estrogen receptor beta
Short name PE, Anti-Estrogen receptor beta
LabelPE
Alternative name peroxidase, antibody to-Estrogen receptor b

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