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Anti-Estrogen Related Receptor gamma, ALEXA Fluor 594

Anti-Estrogen Related Receptor gamma, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideEstrogen Related Receptor gamma
SpecificityThis antibody reacts specifically with Estrogen Related Receptor gamma
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma
Gene ID2104
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information All members of the ESRR family share an almost identical DNA binding domain, It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, Multiple alternatively spliced transcript variants have been identified, The ESRR family is closely related to the estrogen receptor (ER) family, The ESRR members are orphan nuclear receptors, They share target genes, and activate genes controlled by both response elements in the absence of any ligands, and by targeting the same set of genes, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation, co-regulators and promoters, modulates cell proliferation and estrogen signaling in breast cancer, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways, they bind to the estrogen response element and steroidogenic factor 1 response element, which belongs to the nuclear hormone receptor superfamily, which is composed of two C4-type zinc finger motifs, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region, This gene encodes a member of the estrogen receptor-related receptor (ESRR) family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ERR G2, ERR gamma 2, ERR gamma-2, ERR3, ERR3_HUMAN, ERRG 2, ERRG2, ESRRG, Estrogen receptor related protein 3, Estrogen receptor-related protein 3, Estrogen-related receptor gamma, NR3B3, Nuclear receptor subfamily 3 group B member 3, ERR 3
Also known asEstrogen Related Receptor gamma Antibody
Other nameAnti-Estrogen Related Receptor gamma
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetEstrogen Related Receptor gamma
Short name Fluor 594, Anti-Estrogen Receptor gamma
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Estrogen Related Receptor g

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