Name : Anti-ET-2/Endothelin 2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5792703764
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ET-2/Endothelin 2 |
| Specificity | This antibody reacts specifically with ET-2/Endothelin 2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Endolin 2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | 21-amino acid vasoconstrictor peptide, Although ET-3 is expressed as a 238 amino acid peptide, Defects in the gene encoding ET-3 are the cause of a variety of disorders, ET-2 (endothelin-2) and ET-3 (endothelin-3), ET-2 has the most potent vasoconstrictor activity, ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, Endothelins can affect the central nervous system and neuronal excitability, While ET-1 is a potent, and they elicit potent vasoconstrictor action, are vasoactive peptides that are involved in various functions throughout the body, congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4), including Hirschsprung disease type 1 (HSCR1), it is post-translationally modified to produce a short active isoform and a long inactive isoform, mediates the maturation of enteric neurons and melanocytes, through this interaction, which includes ET-1 (endothelin-1), The endothelin (ET) family of proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | EDN2_HUMAN, ET 2, ET-2, ET2, Endothelin 2, Endothelin-2, PPET2, Preproendothelin 2, Preproendothelin-2, EDN2 |
| Also known as | ET-2/Endothelin 2 Polyclonal Antibody |
| Other name | Anti-ET-2/Endothelin 2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ET-2/Endothelin 2 |
| Short name | Anti-ET-2/Endothelin 2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-ET-2/Endothelin 2 (polyclonal) |
| Alternative technique | polyclonals |