Anti-ETHE1 (Polyclonal), ALEXA Fluor 594

Anti-ETHE1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	ETHE1
Specificity	This antibody reacts specifically with ETHE1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human E1
Gene ID	23474
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria, May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm, Suppresses p53-induced apoptosis by preventing nuclear localization of RELA, acrocyanosis, diarrhea, leading to death in the first decade of life, recurrent petechiae, Involvement in disease:Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) , Probably plays an important role in metabolic homeostasis in mitochondria
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	YF13H12 HSCO
Also known as	ETHE1 Polyclonal Antibody
Other name	Anti-ETHE1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	ETHE1
Short name	Anti-ETHE1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-ETHE1 (polyclonal)
Alternative technique	polyclonals
Identity	23287
Gene	ETHE1
Long gene name	ETHE1, persulfide dioxygenase
Synonyms gene name	ethylmalonic encephalopathy 1
Locus	19q13, 31
Discovery year	2003-12-15
Entrez gene record	23474
Pubmed identfication	19136963
RefSeq identity	NM_014297
Havana BLAST/BLAT	OTTHUMG00000182697

Anti-ETHE1 (Polyclonal), ALEXA Fluor 594

Anti-ETHE1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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