Name : Anti-Factor B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1712270109
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Factor B |
| Specificity | This antibody reacts specifically with Factor B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Adipsin, Ba is important in inhibiting the proliferation of preactivated B lymphocytes, Bb combines with complement Factor 3b to produce the C3 or C5 convertase and plays a role in the differentiation and proliferation of preactivated B lymphocytes, Binding of these proteins to their respective G protein-coupled receptors, C1R and C5aR, C3, C3aR, C4 and C5, Complement Factor B, FHR-1 (complement Factor H related protein 1) may play a role in lipid metabolism, Factor H controls the function of the alternative complement pathway, also designated Properdin Factor B or PBF2, also designated complement Factor D, arachidonic acid metabolism, are potent anaphylatoxins that are released during complement activation, cytokine release, induces proinflammatory events, is a serine protease that cleaves complement Factor B and may be involved in obesity, is part of the alternate pathway of the complement system and is cleaved by Factor D into two fragments: Ba and Bb, leukocyte activation and cellular chemotaxis, lysis of erythrocytes, smooth muscle contraction, stimulation of lymphocyte blastogenesis and rapid spreading of peripheral blood monocytes, such as cellular degranulation, The complement component proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FXIIIB |
| Also known as | Factor B Polyclonal Antibody |
| Other name | Anti-Factor B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Factor B |
| Short name | Anti-Factor B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Factor B (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3534 |
| Gene | F13B |
| Long gene name | coagulation factor XIII B chain |
| Synonyms gene name | B polypeptide , coagulation factor XIII |
| Locus | 1q31, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | M14057 |
| Entrez gene record | 2165 |
| Pubmed identfication | 2339067 2271707 |
| RefSeq identity | NM_001994 |
| Classification | Sushi domain containing |
| Havana BLAST/BLAT | OTTHUMG00000036519 |
| Locus Specific Databases | LRG_550 |