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Anti-Factor VIII B chain (Polyclonal), ALEXA Fluor 594

Anti-Factor VIII B chain (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFactor VIII B chain
SpecificityThis antibody reacts specifically with Factor VIII B chain
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Factor VIII B chain
Gene ID2157
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in this gene results in hemophilia A, Jul 2008], This binding domain is essential for coagulant activity, This gene produces two alternatively spliced transcripts, This protein undergoes multiple cleavage events, Transcript variant 1 encodes a large glycoprotein, Transcript variant 2 encodes a putative small protein, [provided by RefSeq, a common recessive X-linked coagulation disorder, converts factor X to the activated form Xa, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, isoform a, isoform b, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex, which consists primarily of the phospholipid binding domain of factor VIIIc, which participates in the intrinsic pathway of blood coagulation, This gene encodes coagulation factor VIII
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms COX8-2 COX8L VIII-L COX VIII
Also known asFactor VIII B chain Polyclonal Antibody
Other nameAnti-Factor VIII B chain Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFactor VIII B chain
Short nameAnti-Factor VIII B chain (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Factor VIII B epitope (polyclonal)
Alternative techniquepolyclonals
Identity 2294
Gene COX8A
Long gene name cytochrome c oxidase subunit 8A
Synonyms gene COX8
Synonyms gene name cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous)
Locus 11q13, 1
Discovery year 1989-06-30
GenBank acession J04823
Entrez gene record 1351
Pubmed identfication 2543673 2847943
RefSeq identity NM_004074
Classification Mitochondrial complex IV: cytochrome c oxidase subunits
Havana BLAST/BLAT OTTHUMG00000167785

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