Name : Anti-FAM21C (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6823718471
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FAM21C |
| Specificity | This antibody reacts specifically with FAM21C |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FAM21C |
| Gene ID | 253725 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Also, FAM21, FAM21 inhibits its anti-capping activity, FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting, FAM21B, FAM21C and FAM21D, Having undergone evolutionary duplication, Putative WASH complex subunit FAM21, by directly interacting with CapZ, four highly homologous family members exist including FAM21A, is a component of the WASH complex, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization, thereby regulating actin dynamics, Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Em:AC012044, 3 KIAA0592 |
| Also known as | FAM21C Polyclonal Antibody |
| Other name | Anti-FAM21C Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FAM21C |
| Short name | Anti-FAM21C (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FAM21C (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 23414 |
| Gene | WASHC2C |
| Long gene name | WASH complex subunit 2C |
| Synonyms gene | FAM21C |
| Synonyms gene name | family with sequence similarity 21 member C |
| Locus | 10q11, 22 |
| Discovery year | 2004-05-27 |
| Entrez gene record | 253725 |
| Pubmed identfication | 20357771 20498093 |
| Classification | WASH complex |
| Havana BLAST/BLAT | OTTHUMG00000018089 |