Name : Anti-FARP2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1849748322
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FARP2 |
| Specificity | This antibody reacts specifically with FARP2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FARP2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Downregulation of the FARP2 gene has been implicated in autism, FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons, It exists as two alternatively spliced isoforms that are abundantly expressed in brain, Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, and testis as well as in embryonic hippocampal and cortical neurons, lung, one DH domain and two PH domains, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion, 545 amino acid protein that contains one FERM domain, FARP2 is a 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0793 FIR PLEKHC3 FRG |
| Also known as | FARP2 Polyclonal Antibody |
| Other name | Anti-FARP2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FARP2 |
| Short name | Anti-FARP2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FARP2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 16460 |
| Gene | FARP2 |
| Long gene name | ARH/RhoGEF and pleckstrin domain protein 2 , FERM |
| Synonyms gene name | FERM, RhoGEF and pleckstrin domain protein 2 |
| Locus | 2q37, 3 |
| Discovery year | 2002-11-29 |
| GenBank acession | AB018336 |
| Entrez gene record | 9855 |
| Pubmed identfication | 9872452 12351724 |
| Classification | Rho guanine nucleotide exchange factors Pleckstrin homology domain containing FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000151574 |