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Anti-Fbx15 (Polyclonal), ALEXA Fluor 594

Anti-Fbx15 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFbx15
SpecificityThis antibody reacts specifically with Fbx15
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Fbx15
Gene ID201456
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO15 can directly interact with Skp1 p19 and CUL-1, FBXO15 is a target of the transcription factor Oct-3/4, IkB-a and b-catenin, In addition, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, Via its F-box domain, also known as FBX15, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, however, immune response, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins, it does not appear to be essential for early development and fertility, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, FBXO15
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC39671 FBX15
Also known asFbx15 Polyclonal Antibody
Other nameAnti-Fbx15 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFbx15
Short nameAnti-Fbx15 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Fbx15 (polyclonal)
Alternative techniquepolyclonals
Identity 13617
Gene FBXO15
Long gene name F-box protein 15
Synonyms gene name F-box only protein 15
Locus 18q22, 3
Discovery year 2003-12-05
GenBank acession AK094215
Entrez gene record 201456
Pubmed identfication 12665572
RefSeq identity NM_152676
Classification F-boxes other
Havana BLAST/BLAT OTTHUMG00000132842

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