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Anti-FBXL11 (Polyclonal), ALEXA Fluor 594

Anti-FBXL11 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFBXL11
SpecificityThis antibody reacts specifically with FBXL11
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FBXL11
Gene ID22992
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Additionally, CXXC8, Expressed ubiquitously with highest expression in testis, F-box proteins are members of a large family that regulate the cell cycle, FBL11, FBL11 functions to demethylate the Lys-36 residue of histone H3, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, KDM2A, Three isoforms of FBL11 exist due to alternative splicing events, also known as FBXL11 (F-box and leucine-rich repeat protein 11), for degradation by the proteasome after ubiquitination, immune response, is a 1, ovary and brain, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby modulating the histone code, 162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1004 FBL11 LILINA DKFZP434M1735 FBL7 FLJ00115 CXXC8 JHDM1A
Also known asFBXL11 Polyclonal Antibody
Other nameAnti-FBXL11 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFBXL11
Short nameAnti-FBXL11 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FBXL11 (polyclonal)
Alternative techniquepolyclonals
Identity 13606
Gene KDM2A
Long gene name lysine demethylase 2A
Synonyms gene FBXL11
Synonyms gene name F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A
Synonyms name F-box protein FBL11 jumonji C domain-containing histone demethylase 1A
Locus 11q13, 2
Discovery year 2000-09-27
GenBank acession BC047486
Entrez gene record 22992
Pubmed identfication 10231032 10531037
RefSeq identity NM_012308
Classification PHD finger proteins Lysine demethylases F-box and leucine rich repeat proteins Zinc fingers CXXC-type
Havana BLAST/BLAT OTTHUMG00000167103

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