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Anti-FBXL20 (Polyclonal), ALEXA Fluor 594

Anti-FBXL20 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFBXL20
SpecificityThis antibody reacts specifically with FBXL20
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FBXL20
Gene ID84961
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information D, FBXL20 has orthologs in C, FBXL20 is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission, FBXL20 is selectively expressed in the brain, SCF complexes, This identifies protein degradation as a mechanism for holding synaptic communication in check, act as protein-ubiquitin ligases, and F-box proteins, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species, broadly expressed within the mouse CNS and is abundant at presynaptic membrane, cullin, elegans, formed by SKP1, melanogaster, which are characterized by an approximately 40-amino acid F-box motif, FBXL20 is a member of the F-box protein family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MGC15482 Fbl2 Fbl20
Also known asFBXL20 Polyclonal Antibody
Other nameAnti-FBXL20 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFBXL20
Short nameAnti-FBXL20 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FBXL20 (polyclonal)
Alternative techniquepolyclonals
Identity 24679
Gene FBXL20
Long gene name F-box and leucine rich repeat protein 20
Locus 17q12
Discovery year 2004-06-15
GenBank acession BC007557
Entrez gene record 84961
Pubmed identfication 12477932
RefSeq identity NM_032875
Classification F-box and leucine rich repeat proteins
Havana BLAST/BLAT OTTHUMG00000179002

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