Name : Anti-FBXL20 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6377269911
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FBXL20 |
| Specificity | This antibody reacts specifically with FBXL20 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FBXL20 |
| Gene ID | 84961 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | D, FBXL20 has orthologs in C, FBXL20 is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission, FBXL20 is selectively expressed in the brain, SCF complexes, This identifies protein degradation as a mechanism for holding synaptic communication in check, act as protein-ubiquitin ligases, and F-box proteins, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species, broadly expressed within the mouse CNS and is abundant at presynaptic membrane, cullin, elegans, formed by SKP1, melanogaster, which are characterized by an approximately 40-amino acid F-box motif, FBXL20 is a member of the F-box protein family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MGC15482 Fbl2 Fbl20 |
| Also known as | FBXL20 Polyclonal Antibody |
| Other name | Anti-FBXL20 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FBXL20 |
| Short name | Anti-FBXL20 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FBXL20 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 24679 |
| Gene | FBXL20 |
| Long gene name | F-box and leucine rich repeat protein 20 |
| Locus | 17q12 |
| Discovery year | 2004-06-15 |
| GenBank acession | BC007557 |
| Entrez gene record | 84961 |
| Pubmed identfication | 12477932 |
| RefSeq identity | NM_032875 |
| Classification | F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT | OTTHUMG00000179002 |