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Anti-FBXL21 (Polyclonal), ALEXA Fluor 594

Anti-FBXL21 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFBXL21
SpecificityThis antibody reacts specifically with FBXL21
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FBXL21/FBL3B
Gene ID26223
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBL3B also contains three LRR (leucine-rich) repeats, FBL3B contains one 40 amino acid F-box region, FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1, FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins, IkB-a and b-catenin, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, FBL3B is a 434 amino acid protein encoded by the human gene FBXL21
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FBL3B Fbl21
Also known asFBXL21 Polyclonal Antibody
Other nameAnti-FBXL21 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFBXL21
Short nameAnti-FBXL21 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FBXL21 (polyclonal)
Alternative techniquepolyclonals
Identity 13600
Gene FBXL21
Long gene name F-box and leucine rich repeat protein 21 (gene/pseudogene)
Synonyms gene FBXL3B FBXL3P
Synonyms gene name F-box and leucine-rich repeat protein 3 pseudogene F-box and leucine-rich repeat protein 21 F-box and leucine-rich repeat protein 21 (gene/pseudogene)
Locus 5q31, 1
Discovery year 2000-09-27
GenBank acession AF129533
Entrez gene record 26223
Pubmed identfication 10531035
RefSeq identity NM_012159
Classification F-box and leucine rich repeat proteins
Havana BLAST/BLAT OTTHUMG00000155971

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