Filters

Anti-FBXO25 (Polyclonal), ALEXA Fluor 594

Anti-FBXO25 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFBXO25
SpecificityThis antibody reacts specifically with FBXO25
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FBXO25
Gene ID26260
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation, Expressed at high levels in brain, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO25 belongs to the Fbxs class, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1, Fbls containing leucine rich repeats, IkB-a and b-catenin, The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), There are three named isoforms produced by alternative splicing, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, also known as FBX25, and Fbxs containing either different protein protein interaction modules or no recognizable motifs, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, the F box, which function in phosphorylation dependent ubiquitination, FBXO25, FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FBX25
Also known asFBXO25 Polyclonal Antibody
Other nameAnti-FBXO25 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFBXO25
Short nameAnti-FBXO25 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FBXO25 (polyclonal)
Alternative techniquepolyclonals
Identity 13596
Gene FBXO25
Long gene name F-box protein 25
Synonyms gene name F-box only protein 25
Locus 8p23, 3
Discovery year 2000-09-27
GenBank acession AF174605
Entrez gene record 26260
Pubmed identfication 10531035 10531037
RefSeq identity NM_012173
Classification F-boxes other
Havana BLAST/BLAT OTTHUMG00000090341

Similar products

Subscribe to our Newsletter