Name : Anti-FBXW5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8329496568
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FBXW5 |
| Specificity | This antibody reacts specifically with FBXW5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FBXW5 |
| Gene ID | 54461 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, FBXW5 contains WD-40 domains, Fbls containing leucine-rich repeats, The F-box proteins are divided into three classes: Fbws containing WD-40 domains, The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), and Fbxs containing either different protein-protein interaction modules or no recognizable motifs, hence not represented, however, in addition to an F-box motif, members of which are characterized by an approximately 40 amino acid motif, so it belongs to the Fbw class, the F-box, they were found to be nonsense-mediated mRNA decay (NMD) candidates, which function in phosphorylation-dependent ubiquitination, FBXW5 is a member of the F-box protein family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DKFZP434B205 MGC20962 Fbw5 |
| Also known as | FBXW5 Polyclonal Antibody |
| Other name | Anti-FBXW5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FBXW5 |
| Short name | Anti-FBXW5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FBXW5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 13613 |
| Gene | FBXW5 |
| Long gene name | F-box and WD repeat domain containing 5 |
| Synonyms gene name | F-box and WD-40 domain protein 5 |
| Locus | 9q34, 3 |
| Discovery year | 2003-06-09 |
| GenBank acession | BC014130 |
| Entrez gene record | 54461 |
| RefSeq identity | NM_018998 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000020967 |