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Anti-FCER1G (Polyclonal), ALEXA Fluor 594
Anti-FCER1G (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489
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BIOSS POLYCLONAL ANTIBODIES
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489
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FCER1G |
| Specificity | This antibody reacts specifically with FCER1G |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human FCER1G |
| Gene ID | 2207 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | (immunoreceptor tyrosine activation motif), Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators such as histamines, ITAM, IgE Fc Receptor I also induces the secretion of important lymphokines, It is a tetramer of a heavily glycosylated alpha chain, Phosphorylation of a pair of conserved tyrosine residues within this motif is required for signal transduction in mast cells and other hemopoietic cell types, The cytoplasmic domains of the beta and gamma subunits each contain a conserved consesus sequence, The gamma chains from Fc epsilon RI are also subunits of other Fc receptors, The gamma subunit is thought to be functionally significant in allowing the IgE Fc receptor to reach the cell surface, a beta chain, and is responsible for initiating the allergic response, and two disulfide linked gamma chains, effectors of the hypersensitivity response, responsible for the manifestations of allergy, IgE Fc Receptor I binds to the Fc region of immunoglobulins epsilon chain with high affinity |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | FCER1G Polyclonal Antibody |
| Other name | Anti-FCER1G Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FCER1G |
| Short name | Anti-FCER1G (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, g polypeptide (polyclonal), high affinity I, receptor to measure, antibody to-fragment c fragment on immunoglobuline E |
| Alternative technique | polyclonals |
| Alternative to gene target | Cell surfaces, FCER1G and IDBG-104229 and ENSG00000158869 and 2207, FCER1G and IDBG-630137 and ENSBTAG00000024503 and 282226, FCRG, Fcer1g and IDBG-204231 and ENSMUSG00000058715 and 14127, IgG binding, engulfment and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010543 and regulation of platelet activation and biological process this GO :0016020 and membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0019767 and IgE receptor activity and molecular function this GO :0019863 and IgE binding and molecular function this GO :0019864 and IgG binding and molecular function this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0030168 and platelet activation and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032765 and positive regulation of mast cell cytokine production and biological process this GO :0032998 and Fc-epsilon receptor I complex and cellular component this GO :0033026 and negative regulation of mast cell apoptotic process and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045576 and mast cell activation and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050778 and positive regulation of immune response and biological process this GO :0050900 and leukocyte migration and biological process this GO :0072659 and protein localization to plasma membrane and biological process, gamma polypeptide, high affinity I, receptor for, this GO :0001798 and positive regulation of type IIa hypersensitivity and biological process this GO :0001805 and positive regulation of type III hypersensitivity and biological process this GO :0001812 and positive regulation of type I hypersensitivity and biological process this GO :0002283 and neutrophil activation involved in immune response and biological process this GO :0002431 and Fc receptor mediated stimulatory signaling pathway and biological process this GO :0002554 and serotonin secretion by platelet and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006911 and pha this GO cytosis, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0019767: IgE receptor activity and also this GO :0019863: IgE binding and also this GO :0019864: IgG binding, this GO :0005515: protein binding, this GO :0019767: IgE receptor activity, this GO :0019863: IgE binding, this GO :0019864: IgG binding, Fc fragment of IgE |
| Identity | 3611 |
| Gene | FCER1G |
| Long gene name | Fc fragment of IgE receptor Ig |
| Synonyms gene name | Fc fragment of IgE, gamma polypeptide , high affinity I, receptor for |
| Synonyms name | Fc epsilon receptor Ig |
| Locus | 1q23, 3 |
| Discovery year | 1990-08-15 |
| Entrez gene record | 2207 |
| Pubmed identfication | 2138619 |
| RefSeq identity | NM_004106 |
| Havana BLAST/BLAT | OTTHUMG00000034343 |