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Anti-FCGRT/FcRn (Polyclonal), ALEXA Fluor 594

Anti-FCGRT/FcRn (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFCGRT/FcRn
SpecificityThis antibody reacts specifically with FCGRT/FcRn
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human FCGRT/FcRn
Gene ID2217
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Brambell receptor, FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, FcRn &, FcRn (also designated FCGRT, FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and â, This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins, chain, thereby helping newborn animals to acquire passive immunity, thus protecting IgG from lysosomal catabolism, #229, &circ, «, -2-Microglobulin, FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FCRN alpha-chain
Also known asFCGRT/FcRn Polyclonal Antibody
Other nameAnti-FCGRT/FcRn Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFCGRT/FcRn
Short nameAnti-FCGRT/FcRn (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, alpha/FcRn (polyclonal), receptor, transporter, antibody to-fragment c fragment on Immunoglobulin G
Alternative techniquepolyclonals
Alternative to gene target FCGRT and IDBG-63001 and ENSG00000104870 and 2217, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, Plasma membranes, alpha, alpha-chain and FCRN, beta-2-microglobulin binding, receptor, this GO :0002416 and IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019864 and IgG binding and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0030881 and beta-2-microglobulin binding and molecular function this GO :0038094 and Fc-gamma receptor signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019864: IgG binding and also this GO :0030881: beta-2-microglobulin binding, this GO :0019864: IgG binding, this GO :0030881: beta-2-microglobulin binding, transporter, Fc fragment of IgG
Identity 3621
Gene FCGRT
Long gene name Fc fragment of IgG receptor and transporter
Synonyms gene name Fc fragment of IgG, alpha , receptor, transporter
Synonyms name heavy chain of the major histocompatibility complex class I-like Fc receptor transmembrane alpha chain of the neonatal receptor
Locus 19q13, 33
Discovery year 1995-08-23
GenBank acession U12255
Entrez gene record 2217
Pubmed identfication 7964511 8646894
Classification C1-set domain containing
Havana BLAST/BLAT OTTHUMG00000183155

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