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Anti-FEZ2/Zygin2 (Polyclonal), ALEXA Fluor 594

Anti-FEZ2/Zygin2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFEZ2/Zygin2
SpecificityThis antibody reacts specifically with FEZ2/Zygin2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FEZ2/Zygin2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information As component of the network of molecules that regulate cellular morphology and axon guidance machinery, Expressed mainly in brain, Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia, PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination, Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short, Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1, elegans UNC-76 mutants, the plasma membrane to the cytoplasm by activation of PKC zeta, which suggest a functional role in axonal outgrowth, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation, Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asFEZ2/Zygin2 Polyclonal Antibody
Other nameAnti-FEZ2/Zygin2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFEZ2/Zygin2
Short nameAnti-FEZ2/Zygin2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-fasciculation and elongation protein zeta 2 (zygin II)/Zygin2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target FEZ2 and IDBG-44299 and ENSG00000171055 and 9637, FEZ2 and IDBG-632353 and ENSBTAG00000009021 and 100299092, Fez2 and IDBG-198635 and ENSMUSG00000056121 and 225020, HUM3CL, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, fasciculation and elongation protein zeta 2 (zygin II)
Identity 3660
Gene FEZ2
Long gene name fasciculation and elongation protein zeta 2
Synonyms name zygin II
Locus 2p22, 2
Discovery year 1999-12-14
GenBank acession U60061
Entrez gene record 9637
Pubmed identfication 9096408
Havana BLAST/BLAT OTTHUMG00000152148

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