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Anti-FIG4/SAC3 (Polyclonal), ALEXA Fluor 594

Anti-FIG4/SAC3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFIG4/SAC3
SpecificityThis antibody reacts specifically with FIG4/SAC3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FIG4
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration, Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), Unlike CMT4J, both of which negatively affect the nervous system, causing paralysis and, death, ultimately, FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SAC3 hSac3 dJ249I4, 1 ALS11 CMT4J
Also known asFIG4/SAC3 Polyclonal Antibody
Other nameAnti-FIG4/SAC3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFIG4/SAC3
Short nameAnti-FIG4/SAC3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FIG4/SAC3 (polyclonal)
Alternative techniquepolyclonals
Identity 16873
Gene FIG4
Long gene name FIG4 phosphoinositide 5-phosphatase
Synonyms gene KIAA0274
Synonyms gene name KIAA0274 FIG4 homolog (S, SAC1 lipid phosphatase domain containing (S, cerevisiae) , cerevisiae) FIG4 homolog
Locus 6q21
Discovery year 2003-11-26
GenBank acession D87464
Entrez gene record 9896
Pubmed identfication 9039502 11274189 17572665
RefSeq identity NM_014845
Classification Phosphoinositide phosphatases
Havana BLAST/BLAT OTTHUMG00000015352
Locus Specific Databases LRG_241

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