Anti-FKBP38 (Polyclonal), ALEXA Fluor 594

Anti-FKBP38 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	FKBP38
Specificity	This antibody reacts specifically with FKBP38
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human FKBP38
Gene ID	23770
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Does not bind and inhibit calcineurin, Forms heterodimer with calmodulin, Highest levels seen in the brain, Homomultimers or heteromultimers (Potential), Interacts with HCV NS5A, Interacts with ZFYVE27, Seems to act as a chaperone for BCL2, The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets, The active form of FKBP8 may therefore play a role in the regulation of apoptosis, When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L), may negatively regulate ZFYVE27 phosphorylation, targets it to the mitochondria and modulates its phosphorylation state, which becomes active when bound to calmodulin and calcium, Constitutively inactive PPiase, Tissue specificity: Widely expressed
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	FKBP38 FKBPr38
Also known as	FKBP38 Polyclonal Antibody
Other name	Anti-FKBP38 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	FKBP38
Short name	Anti-FKBP38 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-FKBP38 (polyclonal)
Alternative technique	polyclonals
Identity	3724
Gene	FKBP8
Long gene name	FK506 binding protein 8
Synonyms gene name	38kDa , FK506-binding protein 8 (38kD) FK506 binding protein 8
Synonyms name	FK506-binding protein 8 (38kD)
Locus	19p13, 11
Discovery year	1999-10-28
GenBank acession	L37033
Entrez gene record	23770
Pubmed identfication	7543869
RefSeq identity	NM_012181
Classification	FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT	OTTHUMG00000183368

Anti-FKBP38 (Polyclonal), ALEXA Fluor 594

Anti-FKBP38 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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