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Anti-FLI1 (Polyclonal), ALEXA Fluor 594

Anti-FLI1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFLI1
SpecificityThis antibody reacts specifically with FLI1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FLI1
Gene ID2313
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A highly malignant, Ewing sarcoma represents the less differentiated form of the tumors, It belongs to the Ewing sarcoma family of tumors, Note=A chromosomal aberration involving FLI1 is found in patients with Erwing sarcoma, Recognizes the DNA sequence 5'-C[CA]GGAAGT-3', They are considered neural tumors derived from cells of the neural crest, Translocation t(11, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents, 22)(q24, Involvement in diseaseDefects in FLI1 are a cause of Ewing sarcoma (ES) , Sequence-specific transcriptional activator, q12) with EWSR1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SIC-1 EWSR2
Also known asFLI1 Polyclonal Antibody
Other nameAnti-FLI1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFLI1
Short nameAnti-FLI1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Friend leukemia virus integration 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007599 and hemostasis and biological process this GO :0008015 and blood circulation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0035855 and megakaryocyte development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, EWSR2 and SIC-1, FLI1 and IDBG-75950 and ENSG00000151702 and 2313, Fli1 and IDBG-147469 and ENSMUSG00000016087 and 14247, nuclei, sequence-specific DNA binding, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0043565: sequence-specific DNA binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0043565: sequence-specific DNA binding, 67771 and IDBG-642793 and ENSBTAG00000008283 and 529124, Friend leukemia virus integration 1
Identity 3749
Gene FLI1
Long gene name ETS transcription factor , Fli-1 proto-oncogene
Synonyms gene name Friend leukemia virus integration 1
Locus 11q24, 3
Discovery year 1991-06-05
GenBank acession M98833
Entrez gene record 2313
Pubmed identfication 1765382
RefSeq identity NM_002017
Classification ETS transcription factor family
Havana BLAST/BLAT OTTHUMG00000165792
Locus Specific Databases LRG_646

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