Name : Anti-FLI1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2978462586
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FLI1 |
| Specificity | This antibody reacts specifically with FLI1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FLI1 |
| Gene ID | 2313 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A highly malignant, Ewing sarcoma represents the less differentiated form of the tumors, It belongs to the Ewing sarcoma family of tumors, Note=A chromosomal aberration involving FLI1 is found in patients with Erwing sarcoma, Recognizes the DNA sequence 5'-C[CA]GGAAGT-3', They are considered neural tumors derived from cells of the neural crest, Translocation t(11, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents, 22)(q24, Involvement in diseaseDefects in FLI1 are a cause of Ewing sarcoma (ES) , Sequence-specific transcriptional activator, q12) with EWSR1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SIC-1 EWSR2 |
| Also known as | FLI1 Polyclonal Antibody |
| Other name | Anti-FLI1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FLI1 |
| Short name | Anti-FLI1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Friend leukemia virus integration 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007599 and hemostasis and biological process this GO :0008015 and blood circulation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0035855 and megakaryocyte development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, EWSR2 and SIC-1, FLI1 and IDBG-75950 and ENSG00000151702 and 2313, Fli1 and IDBG-147469 and ENSMUSG00000016087 and 14247, nuclei, sequence-specific DNA binding, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0043565: sequence-specific DNA binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0043565: sequence-specific DNA binding, 67771 and IDBG-642793 and ENSBTAG00000008283 and 529124, Friend leukemia virus integration 1 |
| Identity | 3749 |
| Gene | FLI1 |
| Long gene name | ETS transcription factor , Fli-1 proto-oncogene |
| Synonyms gene name | Friend leukemia virus integration 1 |
| Locus | 11q24, 3 |
| Discovery year | 1991-06-05 |
| GenBank acession | M98833 |
| Entrez gene record | 2313 |
| Pubmed identfication | 1765382 |
| RefSeq identity | NM_002017 |
| Classification | ETS transcription factor family |
| Havana BLAST/BLAT | OTTHUMG00000165792 |
| Locus Specific Databases | LRG_646 |