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Anti-FMO3 (Polyclonal), ALEXA Fluor 594

Anti-FMO3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFMO3
SpecificityThis antibody reacts specifically with FMO3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FMO3
Gene ID2328
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), FMO1-5, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines, Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, Located in the liver, Through its N-oxygenase capabilities, an inborn error of metabolism associated with a fishy body odor emitting from sweat, that are major enzymatic oxidants involved in the metabolism of various therapeutics, thus producing the malodor associated with TMAuria, urine and breath, The Flavin containing monooxygenase family consists of five gene products
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asFMO3 Polyclonal Antibody
Other nameAnti-FMO3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFMO3
Short nameAnti-FMO3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FMO3 (polyclonal)
Alternative techniquepolyclonals
Identity 3771
Gene FMO3
Long gene name flavin containing monooxygenase 3
Locus 1q24, 3
Discovery year 1992-10-16
GenBank acession BC032016
Entrez gene record 2328
Pubmed identfication 8486388 9417913
RefSeq identity NM_006894
Havana BLAST/BLAT OTTHUMG00000035505
Locus Specific Databases The Homo sapients FMO3 Allelic Variant Database

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