Name : Anti-FMO3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6267133609
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FMO3 |
| Specificity | This antibody reacts specifically with FMO3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FMO3 |
| Gene ID | 2328 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), FMO1-5, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines, Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, Located in the liver, Through its N-oxygenase capabilities, an inborn error of metabolism associated with a fishy body odor emitting from sweat, that are major enzymatic oxidants involved in the metabolism of various therapeutics, thus producing the malodor associated with TMAuria, urine and breath, The Flavin containing monooxygenase family consists of five gene products |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | FMO3 Polyclonal Antibody |
| Other name | Anti-FMO3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FMO3 |
| Short name | Anti-FMO3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FMO3 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3771 |
| Gene | FMO3 |
| Long gene name | flavin containing monooxygenase 3 |
| Locus | 1q24, 3 |
| Discovery year | 1992-10-16 |
| GenBank acession | BC032016 |
| Entrez gene record | 2328 |
| Pubmed identfication | 8486388 9417913 |
| RefSeq identity | NM_006894 |
| Havana BLAST/BLAT | OTTHUMG00000035505 |
| Locus Specific Databases | The Homo sapients FMO3 Allelic Variant Database |