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Anti-FMR2/AFF2, ALEXA Fluor 594

Anti-FMR2/AFF2, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFMR2/AFF2
SpecificityThis antibody reacts specifically with FMR2/AFF2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human AFF2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, Expressed in the brain, FMR2 exists as two isoforms produced by alternative splicing, Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site, an X-linked form of mental retardation, compared to six to thirty-five copies of the GCC repeat in a normal individual, placenta and lung, FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FRAXE
Also known asFMR2/AFF2 Antibody
Other nameAnti-FMR2/AFF2
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetFMR2/AFF2
Short name Fluor 594, Anti-FMR2/AFF2
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FMR2/AFF2
Identity 3776
Gene AFF2
Long gene name AF4/FMR2 family member 2
Synonyms gene FMR2
Synonyms gene name fragile X mental retardation 2 AF4/FMR2 family, member 2
Locus Xq28
Discovery year 2005-06-27
GenBank acession U48436
Entrez gene record 2334
RefSeq identity NM_002025
Classification AF4/FMR2 family Super elongation complex
Havana BLAST/BLAT OTTHUMG00000022613
Locus Specific Databases Mental Retardation database

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