Name : Anti-FOXI1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9225261411
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FOXI1 |
| Specificity | This antibody reacts specifically with FOXI1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FOXI1 |
| Gene ID | 2299 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | FOX transcription factors play important roles in development, FOXI1 functions as a transcription factor, FOXI1 is an upstream transcription regulator of Pendrin (a protein associated with deafness), Localizing to the nucleus, Mice with mutated forms of FOXI1 show defects in ear development, The FOX family is a large group of proteins (consisting of at least 43 members) that share a common DNA binding domain termed winged-helix or forkhead domain, a condition of nonsyndromic hearing loss and enlarged vestibular aqueduct (EVA), aging and hormone responsiveness, differentiation, implying that FOXI1 plays a significant role in the developmental pathway of ears and, in particular, suggesting a role for FOXI1 in the pathogenesis of Pendred syndrome (PS), the cochlea and vestibulum, FOXI1 is a member of the FOX family of transcription factors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FREAC6 |
| Also known as | FOXI1 Polyclonal Antibody |
| Other name | Anti-FOXI1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FOXI1 |
| Short name | Anti-FOXI1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FOXI1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 3815 |
| Gene | FOXI1 |
| Long gene name | forkhead box I1 |
| Synonyms gene | FKHL10 |
| Locus | 5q35, 1 |
| Discovery year | 1995-06-05 |
| GenBank acession | BC029778 |
| Entrez gene record | 2299 |
| Pubmed identfication | 7957066 8825632 |
| RefSeq identity | NM_144769 NM_012188 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000130436 |