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Anti-FOXL2 (Ser263) (Polyclonal), ALEXA Fluor 594

Anti-FOXL2 (Ser263) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFOXL2 Ser263
SpecificityThis antibody reacts specifically with FOXL2 (Ser263)
ModificationPhosphorylation
Modification siteSer263
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263
Gene ID668
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activates SIRT1 transcription under cellular stress conditions, Activates transcription of OSR2, Critical factor essential for ovary differentiation and maintenance, Has apoptotic activity in ovarian cells, Is a regulator of CYP19 expression (By similarity), Is a transcriptional repressor of STAR, Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity), Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity), Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity), and repression of the genetic program for somatic testis determination, Transcriptional regulator
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BPES1
Also known asFOXL2 (Ser263) Polyclonal Antibody
Other nameAnti-FOXL2 (Ser263) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFOXL2 (Ser263)
Short nameAnti-FOXL2 (Ser263) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-forkhead box L2 (Ser263) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BPES and BPES1 and PFRK and PINTO and POF3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0019101 and female somatic sex determination and biological process this GO :0030154 and cell differentiation and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0042703 and menstruation and biological process this GO :0043028 and cysteine-type endopeptidase regulator activity involved in apoptotic process and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048048 and embryonic eye morphogenesis and biological process this GO :0060014 and granulosa cell differentiation and biological process, FOXL2 and IDBG-58706 and ENSG00000183770 and 668, FOXL2 and IDBG-647332 and ENSBTAG00000031277 and 281770, Foxl2 and IDBG-192568 and ENSMUSG00000050397 and 26927, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0002074 and extraocular skeletal muscle development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006355 and regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0030331: estrogen receptor binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0030331: estrogen receptor binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process, this GO :0043565: sequence-specific DNA binding, forkhead box L2
Identity 1092
Gene FOXL2
Long gene name forkhead box L2
Synonyms gene BPES
Locus 3q22, 3
Discovery year 1992-02-28
GenBank acession AF301906
Entrez gene record 668
Pubmed identfication 1941972
Classification Forkhead boxes
Havana BLAST/BLAT OTTHUMG00000159889
Locus Specific Databases Belgium , Ghent, LOVD - Center for Medical Genetics

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