Name : Anti-FOXN1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1742223207
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FOXN1 |
| Specificity | This antibody reacts specifically with FOXN1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human FOXN1 |
| Gene ID | 8456 |
| Swiss Prot | O15353 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A mutation in this gene has been correlated with T-cell immunodeficiency, Alternative splicing in the 5' UTR of this gene has been observed, Jul 2008], This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression, [provided by RefSeq, and nail dystrophy, resulting in a severely compromised immune system, the skin disorder congenital alopecia, Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FKHL20 |
| Also known as | FOXN1 Polyclonal Antibody |
| Other name | Anti-FOXN1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FOXN1 |
| Short name | Anti-FOXN1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-forkhead box N1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006952 and defense response and biological process this GO :0008283 and cell proliferation and biological process this GO :0008544 and epidermis development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0033081 and regulation of T cell differentiation in thymus and biological process this GO :0035878 and nail development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0048538 and thymus development and biological process this GO :0050673 and epithelial cell proliferation and biological process, FKHL20 and RONU and WHN, FOXN1 and IDBG-36752 and ENSG00000109101 and 8456, FOXN1 and IDBG-631668 and ENSBTAG00000013095 and 516724, Foxn1 and IDBG-202803 and ENSMUSG00000002057 and 15218, nuclei, sequence-specific DNA binding, this GO :0001942 and hair follicle development and biological process this GO :0002260 and lymphocyte homeostasis and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0043565: sequence-specific DNA binding, this GO :0043565: sequence-specific DNA binding, forkhead box N1 |
| Identity | 12765 |
| Gene | FOXN1 |
| Long gene name | forkhead box N1 |
| Synonyms gene | WHN RONU |
| Synonyms gene name | winged-helix nude Rowett nude |
| Locus | 17q11, 2 |
| Discovery year | 1998-10-07 |
| GenBank acession | Y11739 |
| Entrez gene record | 8456 |
| Pubmed identfication | 9321431 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000132603 |
| Locus Specific Databases | FOXN1base: Mutation registry for T-cell immunodeficiency, and nail dystrophy (Previously known as WHNbase) LRG_61 , congenital alopecia |