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Anti-FoxO3a (Ser253) (Polyclonal), ALEXA Fluor 594

Anti-FoxO3a (Ser253) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFoxO3a Ser253
SpecificityFoxO3a (Ser253), This phosphorylation site is homologous to Ser252 in Mouse and Rat
ModificationPhosphorylation
Modification siteSer253
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253
Gene ID2309
Swiss ProtO43524
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation, Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3', including neuronal cell death upon oxidative stress, promotes induction of miR-34b and miR-34c expression, Transcriptional activator which triggers apoptosis in the absence of survival factors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms AF6q21, AF6q21 protein, FKHRL1, FKHRL1P2, FOXO3, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1, FOXO2
Also known asFoxO3a (Ser253) Polyclonal Antibody
Other nameAnti-FoxO3a (Ser253) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFoxO3a (Ser253)
Short nameAnti-FoxO3a (Ser253) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FoxO3a (Ser253) (polyclonal)
Alternative techniquepolyclonals

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