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Anti-FREM1 (Polyclonal), ALEXA Fluor 594

Anti-FREM1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFREM1
SpecificityThis antibody reacts specifically with FREM1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human FREM1
Gene ID158326
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation, Hereditary hemorrhagic telangiectasia, Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, Notably, and Familial dysautonomia, are both associated with chromosome 9, chromosome 9 encompasses the largest interferon family gene cluster, encoding nearly 900 genes, one Calx-beta domain and twelve CSPG repeats, which is characterized by harmful vascular defects, 179 amino acid protein that contains one C-type lectin domain, FREM1 is a 2
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ25461 C9orf145 C9orf143 DKFZp686M16108 TILRR
Also known asFREM1 Polyclonal Antibody
Other nameAnti-FREM1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFREM1
Short nameAnti-FREM1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-FRAS1 related extracellular matrix 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target FREM1 and IDBG-50859 and ENSG00000164946 and 158326, FREM1 and IDBG-630756 and ENSBTAG00000020141 and 508018, Frem1 and IDBG-159685 and ENSMUSG00000059049 and 329872, Plasma membranes, metal ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0007154 and cell communication and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0097094 and craniofacial suture morphogenesis and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding and also this GO :0030246: carbohydrate binding and also this GO :0046872: metal ion binding, this GO :0030246: carbohydrate binding, this GO :0046872: metal ion binding, FRAS1 related extracellular matrix 1
Identity 23399
Gene FREM1
Long gene name FRAS1 related extracellular matrix 1
Synonyms gene C9orf154
Synonyms gene name chromosome 9 open reading frame 154
Locus 9p22, 3
Discovery year 2004-04-29
GenBank acession AK058190
Entrez gene record 158326
Pubmed identfication 12838346 15345741
RefSeq identity NM_144966
Classification C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000019575

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