Name : Anti-FREM1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6222077069
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FREM1 |
| Specificity | This antibody reacts specifically with FREM1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FREM1 |
| Gene ID | 158326 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation, Hereditary hemorrhagic telangiectasia, Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, Notably, and Familial dysautonomia, are both associated with chromosome 9, chromosome 9 encompasses the largest interferon family gene cluster, encoding nearly 900 genes, one Calx-beta domain and twelve CSPG repeats, which is characterized by harmful vascular defects, 179 amino acid protein that contains one C-type lectin domain, FREM1 is a 2 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ25461 C9orf145 C9orf143 DKFZp686M16108 TILRR |
| Also known as | FREM1 Polyclonal Antibody |
| Other name | Anti-FREM1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FREM1 |
| Short name | Anti-FREM1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FRAS1 related extracellular matrix 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | FREM1 and IDBG-50859 and ENSG00000164946 and 158326, FREM1 and IDBG-630756 and ENSBTAG00000020141 and 508018, Frem1 and IDBG-159685 and ENSMUSG00000059049 and 329872, Plasma membranes, metal ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0007154 and cell communication and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0097094 and craniofacial suture morphogenesis and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding and also this GO :0030246: carbohydrate binding and also this GO :0046872: metal ion binding, this GO :0030246: carbohydrate binding, this GO :0046872: metal ion binding, FRAS1 related extracellular matrix 1 |
| Identity | 23399 |
| Gene | FREM1 |
| Long gene name | FRAS1 related extracellular matrix 1 |
| Synonyms gene | C9orf154 |
| Synonyms gene name | chromosome 9 open reading frame 154 |
| Locus | 9p22, 3 |
| Discovery year | 2004-04-29 |
| GenBank acession | AK058190 |
| Entrez gene record | 158326 |
| Pubmed identfication | 12838346 15345741 |
| RefSeq identity | NM_144966 |
| Classification | C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000019575 |