Anti-Frizzled 5/8 (Polyclonal), ALEXA Fluor 594

Anti-Frizzled 5/8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Frizzled 5/8
Specificity	This antibody reacts specifically with Frizzled 5/8
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human Frizzled 5
Gene ID	7855, 8325
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes, Coreceptor along with RYK of Wnt proteins, ESTs have been isolated from bone, Frizzled 5 has been reported to be expressed in fetal kidney, Frizzled 5 was cloned from a retina cDNA library, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Receptor for Wnt proteins, The Frizzled 5 protein is believed to be the receptor for the Wnt5A ligand, The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, and adult pancreas, and prostate libraries, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, fetal and adult liver, fetal lung, inhibition of GSK-3 kinase, liver/spleen, nuclear accumulation of beta-catenin and activation of Wnt target genes, placenta, such as WNT1, Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	FZD 5, FZD5, FZD5_HUMAN, FZD8, Frizzled homolog 5, Frizzled-5, Frizzled-8, Frizzled5, Fz 5, Fz-5, Fz-8, Fz5, FzE 5, FzE5, HFZ 5, Seven transmembrane receptor frizzled 5, Wnt receptor, hFz5, hFz8, C2orf31
Also known as	Frizzled 5/8 Polyclonal Antibody
Other name	Anti-Frizzled 5/8 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Frizzled 5/8
Short name	Anti-Frizzled 5/8 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Frizzled 5/8 (polyclonal)
Alternative technique	polyclonals

Anti-Frizzled 5/8 (Polyclonal), ALEXA Fluor 594

Anti-Frizzled 5/8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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