Name : Anti-FRMD8 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9925691789
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FRMD8 |
| Specificity | This antibody reacts specifically with FRMD8 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human FRMD8 |
| Gene ID | 83786 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Existing as two alternatively spliced isoforms, FRMD8 (FERM domain-containing protein 8), Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Moesin and 4, Niemann-Pick disease, Radixin, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, With approximately 135 million base pairs and 1, also known as FKSG44, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 464 amino acid protein containing one FERM domain, the gene encoding FRMD8 maps to human chromosome 11q13, where they provide a link between cytoskeletal signals and membrane dynamics, 1, 1 (erythrocyte membrane protein band 4, 1), 400 genes, FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ90369 FKSG44 |
| Also known as | FRMD8 Polyclonal Antibody |
| Other name | Anti-FRMD8 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FRMD8 |
| Short name | Anti-FRMD8 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FRMD8 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25462 |
| Gene | FRMD8 |
| Long gene name | FERM domain containing 8 |
| Locus | 11q13, 1 |
| Discovery year | 2007-08-14 |
| GenBank acession | AK074850 |
| Entrez gene record | 83786 |
| Pubmed identfication | 12477932 |
| RefSeq identity | NM_031904 |
| Classification | FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166275 |