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Anti-FTO (Polyclonal), ALEXA Fluor 594

Anti-FTO (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFTO
SpecificityThis antibody reacts specifically with FTO
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human Fat mass and obesity-associated protein
Gene ID79068
Swiss ProtQ9C0B1
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Contributes to the regulation of body size and body fat accumulation, Contributes to the regulation of the global metabolic rate, Has highest activity towards single-stranded RNA containing 3-methyluracil, Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine, Has no activity towards 1-methylguanine, Has no detectable activity towards double-stranded DNA, Requires molecular oxygen, Specifically demethylates N(6)-methyladenosine (m6A) RNA, alpha-ketoglutarate and iron, energy expenditure and energy homeostasis, followed by single-stranded DNA containing 3-methylthymine, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes, Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1752 MGC5149 ALKBH9
Also known asFTO Polyclonal Antibody
Other nameAnti-FTO Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFTO
Short nameAnti-FTO (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-fat mass and obesity associated (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DNA-N1-methyladenine dioxygenase activity, FTO and IDBG-31147 and ENSG00000140718 and 79068, FTO and IDBG-631892 and ENSBTAG00000012501 and 618622, Fto and IDBG-179938 and ENSMUSG00000055932 and 26383, nuclei, this GO :0001659 and temperature homeostasis and biological process this GO :0005634 and nucleus and cellular component this GO :0006307 and DNA dealkylation involved in DNA repair and biological process this GO :0008198 and ferrous iron binding and molecular function this GO :0010883 and regulation of lipid storage and biological process this GO :0016607 and nuclear speck and cellular component this GO :0035515 and oxidative RNA demethylase activity and molecular function this GO :0035516 and oxidative DNA demethylase activity and molecular function this GO :0035552 and oxidative single-stranded DNA demethylation and biological process this GO :0035553 and oxidative single-stranded RNA demethylation and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042245 and RNA repair and biological process this GO :0043734 and DNA-N1-methyladenine dioxygenase activity and molecular function this GO :0044065 and regulation of respiratory system process and biological process this GO :0060612 and adipose tissue development and biological process this GO :0070350 and regulation of white fat cell proliferation and biological process this GO :0070989 and oxidative demethylation and biological process this GO :0080111 and DNA demethylation and biological process, this GO :0008198: ferrous iron binding, this GO :0008198: ferrous iron binding and also this GO :0035515: oxidative RNA demethylase activity and also this GO :0035516: oxidative DNA demethylase activity and also this GO :0043734: DNA-N1-methyladenine dioxygenase activity, this GO :0035515: oxidative RNA demethylase activity, this GO :0035516: oxidative DNA demethylase activity, this GO :0043734: DNA-N1-methyladenine dioxygenase activity, fat mass and obesity associated
Identity 24678
Gene FTO
Long gene name FTO, alpha-ketoglutarate dependent dioxygenase
Synonyms gene name fat mass and obesity associated
Synonyms name alkB homolog 9 alpha-ketoglutarate-dependent dioxygenase
Locus 16q12, 2
Discovery year 2007-04-12
GenBank acession BC003583
Entrez gene record 79068
Pubmed identfication 17434869 17991826 22002720
RefSeq identity NM_001080432
Classification Alkylation repair homologs
Havana BLAST/BLAT OTTHUMG00000158780

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