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Anti-Fukutin (Polyclonal), ALEXA Fluor 594

Anti-Fukutin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideFukutin
SpecificityThis antibody reacts specifically with Fukutin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Fukutin
Gene ID282969
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information FCMD is the first human disease known to be caused by an ancient retrotransposal integration, Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, Fukutin deficiency affects the modification of glycosylation of DAG1 (Î, Fukutin may be located in the extracellular matrix, The fukutin gene is expressed at similar levels in control fetal and adult brain, The gene which encodes fukutin maps to human chromosome 9q31, a secreted protein, alternatively, as a secreted protein, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains, fukutin may cause muscular dystrophy by an unknown mechanism, is expressed in various tissues in normal individuals, suggesting that fukutin passes through the Golgi before being packaged into secretory vesicles, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes, which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber, ±, -dystroglycan), Fukutin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LGMD2I MDC1C
Also known asFukutin Polyclonal Antibody
Other nameAnti-Fukutin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetFukutin
Short nameAnti-Fukutin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Fukutin (polyclonal)
Alternative techniquepolyclonals
Identity 17997
Gene FKRP
Long gene name fukutin related protein
Locus 19q13, 32
Discovery year 2003-12-04
GenBank acession AJ314847
Entrez gene record 79147
Pubmed identfication 11592034 11741828
RefSeq identity NM_024301
Havana BLAST/BLAT OTTHUMG00000183177
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_761

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