Name : Anti-FXYD6 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3516362832
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | FXYD6 |
| Specificity | This antibody reacts specifically with FXYD6 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human FXYD6 |
| Gene ID | 53826 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | After expression, FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, FXYD4 (CHIF) and FXYD5 (RIC), FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase, FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons, FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, Members of the FXYD family include FXYD1 (PLM, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids, mammary tumor protein), muscle contraction and neuronal excitability, phospholemman), which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase, The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | FXYD6 Polyclonal Antibody |
| Other name | Anti-FXYD6 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | FXYD6 |
| Short name | Anti-FXYD6 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-FXYD6 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 4030 |
| Gene | FXYD6 |
| Long gene name | FXYD domain containing ion transport regulator 6 |
| Synonyms gene name | FXYD domain-containing ion transport regulator 6 |
| Synonyms name | phosphohippolin |
| Locus | 11q23, 3 |
| Discovery year | 2000-05-23 |
| GenBank acession | BC093040 |
| Entrez gene record | 53826 |
| Pubmed identfication | 10950925 |
| RefSeq identity | NM_022003 |
| Havana BLAST/BLAT | OTTHUMG00000166991 |